In recent years, botulinum toxin preparations have gained popularity as a means of smoothing out expression lines — wrinkles caused by excessive activity of the facial muscles. But is Botox really dangerous, and what do we actually know about it?
Xeomin has been used in clinical practice for more than 10 years, with over 127,000 people having received injections of this drug, and to date, not a single patient has been identified who failed to show a secondary clinical response.
An in-depth analysis of the lack of effect of botulinum toxin type A treatment and the decline in its efficacy with long-term use. Causes of nonresponse or reduced effect with prolonged administration.
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